Spermidine is a naturally occurring polyamine found in all living cells. It plays a crucial role in cellular growth, repair, and longevity. This compound is involved in a biological process known as autophagy, where the body cleans out damaged cells and regenerates healthier ones. Named after its initial discovery in semen, spermidine is also abundant in various foods and tissues, making it a key molecule in maintaining health at the cellular level.

With its ability to support cellular renewal, spermidine has gained attention for its potential anti-aging and health-promoting properties.

Why Is Spermidine Important to Our Health?

Spermidine is vital for maintaining cellular health and longevity. Its benefits include:

• Autophagy Activation: Spermidine induces autophagy, helping the body clear out damaged cells and reduce the accumulation of toxins, which is essential for preventing age-related diseases.
• Anti-Aging Effects: By supporting cellular renewal, spermidine may slow aging processes and improve skin, hair, and overall vitality.
• Brain Health: It has neuroprotective properties and may enhance cognitive function by reducing oxidative stress and supporting brain cell health.
• Cardiovascular Health: Spermidine has been linked to improved heart health by promoting vascular elasticity and reducing inflammation.
• Immune System Support: It enhances the body’s ability to fight infections and maintain a robust immune response.

A decline in spermidine levels as we age underscores its importance in sustaining long-term health.

How Can You Increase Your Spermidine Levels Naturally?

Spermidine can be found in several foods, including:

• Wheat Germ: One of the richest natural sources.
• Soy Products: Tofu, natto, and soybeans.
• Cheese: Aged varieties like Parmesan.
• Legumes: Lentils and chickpeas.
• Mushrooms: Particularly shiitake mushrooms.
• Green Vegetables: Such as broccoli and green peppers.

Including these foods in your diet can help boost spermidine levels naturally. Regular consumption of a spermidine-rich diet is a simple way to promote cellular health.

Why Do People Take Spermidine as a Supplement?

Despite its presence in foods, maintaining optimal spermidine levels through diet alone can be challenging, especially as levels naturally decline with age. Supplements provide a concentrated, consistent source of spermidine, making it easier to reap its health benefits.

Common reasons for supplementation include:

• Anti-Aging: To support cellular renewal and combat signs of aging.
• Cognitive Support: To enhance memory, focus, and brain health.
• Heart Health: To promote cardiovascular wellness.
• Immune Boosting: To improve the body’s resilience against illness.

For faster and more efficient absorption, many opt for IV spermidine treatments.

A Summary of the Evidence That Exists for Supplemental IV Spermidine Effectiveness

Studies show that spermidine supplementation can effectively activate autophagy and support cellular health. Research published in Nature Aging highlights spermidine’s potential to extend lifespan and improve healthspan by rejuvenating cells. Additional studies in Cell Reports suggest spermidine’s role in brain health and its protective effects against neurodegenerative conditions.

IV spermidine, by bypassing digestion, ensures rapid and efficient absorption, allowing individuals to benefit from its cellular renewal properties more directly. While more clinical research is ongoing, early findings are promising.

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Alchemy by Effect Doctors offers premium IV spermidine treatments tailored to your health goals. We are as a team very excited by the purported anti aging properties of this cutting edge supplement. Whether you’re seeking to enhance vitality, support brain function, or promote longevity, our expert team is here to help. Contact us today to learn how IV spermidine can support your journey to optimal health.

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme found in every cell of the body. It plays a central role in energy metabolism and is vital for cellular repair, immune function, and maintaining overall health. NAD+ facilitates the conversion of nutrients into energy and supports the function of key enzymes called sirtuins, which regulate aging, stress response, and DNA repair.

Unfortunately, NAD+ levels naturally decline with age and are further depleted by stress, illness, poor lifestyle choices, and environmental toxins. This decline has been linked to fatigue, cognitive decline, and an increased risk of age-related diseases, making NAD+ replenishment an area of significant scientific interest (Nature Reviews Molecular Cell Biology, PMID: 36118157).

Why is NAD+ Important to Our Health?

NAD+ is often referred to as a “youth molecule” because of its far-reaching benefits:

• Cellular Energy Production: NAD+ is essential for converting food into usable energy through cellular respiration. Without it, energy production declines, leading to fatigue and reduced vitality.
• DNA Repair and Cellular Longevity: NAD+ activates enzymes like PARPs and sirtuins, which play a critical role in repairing DNA damage and promoting cellular health (Molecular Cell, PMID: 36170435).
• Brain Health: NAD+ supports neuronal function, memory, and cognition by protecting against oxidative stress and mitochondrial dysfunction. Low levels are associated with neurodegenerative conditions such as Alzheimer’s disease (Neurobiology of Aging, PMID: 31917996).
• Immune Function: NAD+ plays a vital role in modulating inflammation and maintaining a healthy immune response, especially during illness or infection (Frontiers in Immunology, PMID: 34530866).

Declining NAD+ levels are linked to aging, metabolic disorders, and chronic diseases, underscoring the importance of maintaining optimal levels.

How Can You Increase Your NAD+ Levels Naturally?

Though the body produces NAD+ naturally, these levels decrease with age. Fortunately, you can support NAD+ levels through:

• Diet: Foods rich in vitamin B3 (niacin), such as turkey, salmon, peanuts, and avocados, can support NAD+ production.
• Exercise: Regular physical activity stimulates NAD+ biosynthesis and enhances mitochondrial health.
• Intermittent Fasting or Caloric Restriction: Studies show that fasting and reduced caloric intake can increase NAD+ levels by activating key metabolic pathways (Journal of Clinical Investigation, PMID: 36118157).
• Supplements: NAD+ precursors such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) are popular options for boosting NAD+ levels.

Why Do People Take NAD+ as a Supplement or Therapy?

NAD+ supplementation has gained popularity as a way to combat aging, enhance energy, and support recovery. While oral precursors like NMN and NR are effective, IV NAD+ therapy offers unique benefits:

• Immediate Absorption: By bypassing the digestive system, IV NAD+ delivers the coenzyme directly into the bloodstream for rapid replenishment.
• Cellular Repair and Detoxification: IV therapy can accelerate recovery from stress, illness, and toxin exposure.
• Energy and Vitality: Many individuals report increased energy, improved focus, and better mood following IV NAD+ therapy.

A Summary of the Evidence for NAD+ Supplementation

Scientific research strongly supports the benefits of NAD+ for a range of health outcomes:

1. Anti-Aging and Longevity: Studies show that boosting NAD+ levels can slow cellular aging and improve mitochondrial function, supporting long-term health (Nature Reviews Molecular Cell Biology, PMID: 36118157).
2. Cognitive Function: NAD+ supplementation has been shown to improve memory, focus, and overall brain health, particularly in neurodegenerative conditions (Neurobiology of Aging, PMID: 31917996).
3. Immune Health: Research highlights NAD+ as a key modulator of inflammation, helping to combat infection and reduce chronic disease risk (Frontiers in Immunology, PMID: 34530866).
4. Metabolic Support: NAD+ improves energy metabolism and insulin sensitivity, making it a promising option for addressing metabolic disorders like obesity and diabetes (Cell Metabolism, PMID: 37971292).
5. Recovery from Stress and Illness: IV NAD+ therapy has been reported to support detoxification, reduce fatigue, and enhance cellular repair mechanisms, especially after periods of physical or emotional stress (Molecular Cell, PMID: 36170435).

At Alchemy by Effect Doctors, we offer cutting-edge IV NAD+ therapy designed to restore your vitality and support cellular health. Whether you’re looking to boost energy, slow the effects of aging, or recover from stress, our expert team delivers safe and personalized treatments. Contact us today to learn more about how NAD+ therapy can elevate your health and well-being.

You can find NAD+ in our following products:

NAD+ IV Therapy

Limitless NAD IV